Cyclodextrin nanosponges are novel highly cross-linked cyclodextrin nanoporous polymer. These are prepared by reacting cyclodextrin (CD) with several cross linking agents such as carbamate (Isocyanates), carbonate (carbonyl diimidazole, Diphenyl carbonate), ester (Maleic anhydride, Pyromellitic dianhydride) and polyamidoamine compounds. They are spherical, crystalline or paracrystalline, porous, nontoxic, nonhemolytic and stable solid nanoparticles. They can be used as carriers for lipophilic and hydrophilic drugs. They can also decrease side effects and protect drugs from degradation.
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